The studies included 61 healthy individuals aged 20–60 who were assessed in relation to the occurrence of Candida yeast carriage. Fungal culture and identification were conducted according to the standard procedures. Evaluation of fungicidal operation of nanosilver was carried out against the isolated strains of Candidagenus and the reference strain. During the study, the modi-fied dilution-neutralization method was applied according to the PN-EN 1275. Swab samples collected from the skin of the lower extremities of 10 people (15.8%) was positive for the presence of fungi. The present studies showed that among the recovered yeasts, the pres-ence of C. albicans and C. guiliermondiiwas observed as well as single cases of C. parapsilosis, C. famata and C. lusitania. All the tested strains proved to be susceptible to nanosilver applica-tion, i.e. all the studied strains exhibited the reuction in viable cell counts within 60 min of expo-sure time.