The aim of the study was to characterize the occurrence of salmonellosis in the opera-tion area of the State Sanitary- Epidemiological Station in Zamosc (PSSE) in 2013 and 2014.The scope of the research included the Zamosc city and county residents. The data came from the archives of the PSSE. All cases were documented. The main etiological agent of the disease was Salmonella enteritidis, which accounted for 88.8% of the totalnumber of cases in 2013 and 87.5% in2014, respectively. Most cases were reported in the youngest age groupof cases(30.8%) in that time interval. It is important to note that in 2013 and 2014thenumber of salmonellosis cases showed a downward trend from 18 to 8.