Improvement in globe artichoke in climatic conditions of Poland can be achieved by drip irrigation of plants. Different levels of drip irrigation were applied: full irrigation (I100), 75% of I100 (I75), 50% of I100 (I50), and no irrigation (I0), to evaluate yield and polyphenolic content in leaves. Irrigation during the whole cultivation period increased yield. The chemical analysis of the composition of globe artichoke leaves showed variation in the determined components depending on irrigation regimes. More total phenolic compounds, expressed as gallic acid equivalents, were found in leaves harvested from plants that were not irrigated. Chlorogenic acid represented the major family of phenolic compounds in artichoke extracts, especially during water shortage, accounting for 772.2 mg 100‑1 g DM. During water shortage, 1,3-dicaffeoylquinic, 3,4-dicaffeoylquinic and 3,5-dicaffeoylquinic acids increased. The highest content of apigenin and luteolin was found under optimal water and air conditions due to improvement in soil moisture content. Our study shows that there are prospects for practical application of irrigation in artichoke cultivation in order to modify bioactive substances