Potential role of natural products to combat radiotherapy and their future perspectives

Abstrakt

Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy (RT) are the common cancer treatments. In addition to these limitations, the development of adverse effects from chemotherapy and RT reduces the quality of life for cancer patients. Cellular radiosensitivity, or the ability to resist and overcome cell damage caused by ionizing radiation (IR), is directly related to cancer cells’ response to RT. Therefore, radiobiological research is emphasizing chemical compounds ’radiosensitization of cancer cells so that they are more reactive in the IR spectrum. Recent years researchers have seen an increase in interest in natural products that have antitumor effects with minimal side effects. Natural products, on the other hand, are easy to recover and therefore less expensive. There have been several scientific studies done based on these compounds that have tested their ability in vitro and in vivo to induce tumor radiosensitization. The role of natural products in RT, as well as their usefulness and potential applications, is the goal of this current review.

Autorzy

Rokeya Akter
Rokeya Akter
Habibur Rahman
Habibur Rahman
Muddaser Shah
Muddaser Shah
Syed Shams Ul Hassan
Syed Shams Ul Hassan
Sidra Mubin
Sidra Mubin
Parveen Bibi
Parveen Bibi
Saeeda Saeeda
Saeeda Saeeda
artykuł
MOLECULES
Angielski
2021
26
19
5997
otwarte czasopismo
CC BY 4.0 Uznanie autorstwa 4.0
ostateczna wersja opublikowana
w momencie opublikowania
2021-10-02
140
4,927
0
15