Malaria is a significant disease that affects both animals and humans. The four main Plasmodium species that
cause human malaria are Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, and Plasmodium
ovale. Plasmodium knowlesi, a parasite typically infecting forest macaque monkeys, was recently revealed to
be able to be transmitted by anophelines and provoke malaria in humans. This provides an increasing risk
of spreading the disease to areas previously unaffected with it and infecting people during the increasingly
popular travels abroad. Microscopic examination remains one of the most often used methods for its laboratory
confirmation. These tests, however, should be performed immediately after receiving samples from a firstcontact doctor to allow immediate therapy. This research presents a novel, semantic segmentation neural
network architecture designed to quickly create a classification mask, giving the doctor information about
the position, shape, and possible affiliation of detected elements. The evaluation method is based on a light
microscope imagery and was created to overcome problems resulting from the human diagnosis specifics. There
are 3 abstract classes containing healthy cells, cells with malaria and background. The outputted mask can
be later mapped to a more readable form with the inclusion of contrasting colors, next to an original image
for quick validation. Such an approach allows for semi-automatic recognition of possible disease, nevertheless
still giving the final verdict to the specialist. The developed solution has achieved a high recognition accuracy
of 96.65%, while the computer power requirements are kept at a minimum. The proposed solution can help
reduce misclassification rates by providing additional data for the doctor and speed up the entire process with
the early diagnosis made by a deep learning model.