The family Phenuiviridae (Bunyavirales), harbors of negative-strand RNA viruses
infecting three kingdoms of host organisms: humans and animals, plants and
fungi, which is rare in known virus families. Animals, humans, and arthropods
serve as natural hosts. Many phenuiviruses are arboviruses and replicate in two
distinct hosts - insects and humans or insects and plants. Ticks are the primary
vectors for pathogens of domesticated and wild animals and the secondary
vectors for pathogens of humans. Multiple phenuivirid species, such as Alenquer
virus, Kabuto virus, Bhanja virus, Chandiru virus, Heartland virus, Rift Valley fever
virus, Punta Toro virus, Sandfly fever virus, Severe fever with thrombocytopenia,
they all are pathogenic for humans. This review draws a panorama for the
virus family Phenuiviridae of importance for humans and animals. Moreover,
epidemiology, and diagnosis of Phenuiviruses are shortly reviewed