Morel’s disease is a specific lymphadenitis of sheep and goats caused by Staphylococcus aureus subsp. anaerobius. It is characterized by abscesses formation near the lymph nodes: mandibular, parotid and lateral retropharyngeal, followed by superficial cervical, subiliac and popliteal lymph nodes. In the flock, morbidity rate is high and disease affects mainly young animals up to 5–6 months of age. Morel’s disease is prevailing in some African and Asian countries. There are also reports on the outbreaks in European countries, including Poland. The economic losses include carcasses condemnation, decline in milk production, and weight gain, also reduced value of skins due to scarring. The total costs of Morel’s disease are complemented with drugs and labor expenses needed to treat superficial abscesses. Losses are increased when the affected lymph nodes are in critical area, as jaw, crural region and udder, negatively affecting chewing and locomotion. Contagious, chronic and generally subclinical nature of the disease and inefficiency of drug therapy, together with lack of vaccines, make the control of Morel’s disease quite difficult