The primary objective of this research was to enhance the quality of semantic segmentation in cytology images by incorporating super-resolution (SR) architectures. An additional contribution was the development of a novel dataset aimed at improving imaging quality in the presence of inaccurate focus. Our experimental results demonstrate that the integration of SR techniques into the segmentation pipeline can lead to a significant improvement of up to 25% in the mean average precision (mAP) metric. These findings suggest that leveraging SR architectures holds great promise for advancing the state-of-the-art in cytology image analysis.